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Brilliant Minds

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A gifted neurologist and his team of bright young interns apply an unconventional approach to treating the world’s most puzzling psychological cases.

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Brilliant Minds

Zachary Quinto stars as an eccentric yet incredibly gifted neurologist in this intriguing new medical drama. His rare condition - face blindness - gives him a unique perspective on care, fueling his mission to change the way people see his patients. Alongside a team of brilliant young interns, he’ll solve some of the world’s most puzzling psychological cases while navigating the complicated relationships that come with the job.

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Starring: Zachary Quinto, Tamberla Perry, Ashleigh LaThrop, Alex MacNicoll, Aury Krebs, Spence Moore II, Teddy Sears, Donna Murphy, John Clarence Stewart, Brian Altemus, Al Calderon

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The Phantom Hook
S2 E1 • 42M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf helps an MMA fighter with mysterious symptoms; Dr. Pierce ponders leaving Bronx General.

The Contestant
S2 E2 • 42M • HDAudio DescribedClosed CaptionedTV14

A reality show contestant comes in with an unusual delusion; Dr. Pierce fights for her future.

The Pusher
S2 E3 • 42M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf and his team treat a young patient accused of a serious crime.

Lady Liberty
S2 E4 • 42M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf and Dr. Pierce are tasked with a house call to evaluate a woman under a conservatorship.

Once Upon a Time in America
S2 E5 • 42M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf and Dr. Nichols must do whatever it takes to keep two patients in critical condition alive.

The Doctor's Graveyard
S2 E6 • 42M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf is haunted by a ghost from his past; a patient appears to have risen from the dead.

The One That Got Away
S2 E7 • 42M • HDAudio DescribedClosed CaptionedTV14

A blast from the past shakes up Dr. Wolf's world when he becomes his next patient.

The Upside Down
S2 E8 • 42M • HDAudio DescribedClosed CaptionedTV14

On a flight gone wrong, one patient's life is literally turned upside down.

The Fire Fighter
S2 E9 • 42M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf helps a firefighter and his family navigate a life-changing diagnosis on Thanksgiving.

The Resident
S2 E10 • 42M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf helps a ballerina recover after a mystery illness; the team tries to save Sam's life.

The Boy Who Feels Everything
S2 E11 • 42M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf and the team come together as one of their own fights for their life.

The Rider
S2 E12 • 42M • HDAudio DescribedClosed CaptionedTV14

A rugged cowboy struts into Bronx General with mysterious symptoms and brings the rodeo with him.

The Rabbit Hole
S2 E13 • 41M • HDAudio DescribedClosed CaptionedTV14

Dr. Wolf and team learn about sorority life while treating a gravely ill college student.

The Invisible Man
S2 E14 • 42M • HDAudio DescribedClosed CaptionedTV14

A grisly accident endangers everyone at Bronx General and leads to a shocking revelation about Wolf.

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Season 2 of Brilliant Minds premiered September 22, 2025.
Brilliant Minds follows Dr. Oliver Wolf (Zachary Quinto), a revolutionary neurologist at Bronx General Hospital. Inspired by the real cases of Oliver Sacks, the show blends medical mysteries with deeply human stories about relationships and mental health.
The cast of Brilliant Minds Season 2 features Zachary Quinto as Dr. Oliver Wolf, Tamberla Perry as Dr. Carol Pierce, Ashleigh LaThrop as Ericka Kinney, Alex MacNicoll as Dr. Van Markus, Aury Krebs as Dr. Dana Dang, Spence Moore II as Dr. Jacob Nash, Teddy Sears as Dr. Josh Nichols, and Donna Murphy as Dr. Muriel Landon.

New series regulars joining the ensemble include Brian Altemus as Charlier Porter, John Clarence Stewart as Anthony Thorne, and Al Calderon as Nurse Scotty Silva. Season 2 also welcomed guest stars such as Bellamy Young, Porsha Williams, Laura Vandervoort, Molly Bernard, and Connor Tomlinson.